Central Zone Office, latest amongst all Zonal Offices opened in February 1995 at Bhopal. Central Zone comprises of three states namely, Chhattisgarh, Madhya Pradesh and Rajasthan. Major categories of industries include Thermal Power Plants, Cement, Distilleries, Pharmaceuticals, sponge iron and pulp & paper. Mining activities are done extensively in entire zone including coal, limestone, copper, zinc, quartz and other minerals. Soya bean processing units in MP, rice mills in Chhattisgarh and textile processing, dyeing and printing units in Rajasthan are other specific industries.
The Activities taken up at Zonal Office, Bhopal include preparation of Environment Status Reports, Industry Specific Reports, Area Specific Reports and Performance Evaluation Reports on Common Effluent Treatment Plants, Sewage Treatment Plants, Common Hazardous Waste TSDFs and Common Biomedical Waste Treatment Facilities.

Other important activities are inspection and monitoring of industries under 17 categories; inspections carried out along with the Regional Offices of Ministry of Environment and Forests, investigations of public complaints with VIP reference, surprise inspections under Environmental Surveillance Squad activities, inspections of monitoring stations under NAMP and NWMP programmes, conducting mass awareness programmes and imparting training to the target groups.

The Zonal Office has 25 officials working at Bhopal, 16 of them from scientific and technical streams. The laboratory attached to the office is equipped to analyse all the essential physico-chemical parameters including advance instrument Atomic Absorption Spectro-Photometer. The office has the latest monitoring equipment for ambient air, source emissions and noise.